MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL

Catalog number BNUB1729-100

Price for BNUB1729-100

Size / count 1x 100 µL

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB1729-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MMP3; Proteoglycanase; SL1; STMY1; STR1; Stromelysin-1; Transin 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MMP3
Gene ID: 4314
NCBI Gene ID: 375129
UniProt: P08254
Swiss Prot: P08254
Host: Mouse
Species Reactivity: Human
Reactivity: MMP3
Immunogen: Recombinant fragment corresponding to amino acids 317-327 of human MMP3.
Target Antigen: MMP3
Clonality: Monoclonal
Clone: 1B4
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (published) |WB (published)
Positive Control: A431 cells. Prostate or Lung Carcinoma.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: 57 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Clin Cancer Res (2006) 12(4) 1184-1191. (IHC, FFPE) Placenta (2010) 31(10): 886-892. (WB)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL?

The catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL is BNUB1729-100.

What sizes are available for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL in stock?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL?

Estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL?

The safety data sheet for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (1B4), 0.2mg/mL used for?

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.