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Product details

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL

Catalog number BNC041730-100

Price for BNC041730-100

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Size / count 1x 100 µL

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC041730-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MMP3; Proteoglycanase; SL1; STMY1; STR1; Stromelysin-1; Transin 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MMP3
Gene ID
4314
NCBI Gene ID
375129
UniProt
P08254
Swiss Prot
P08254
Host
Mouse
Species Reactivity
Human
Reactivity
MMP3
Immunogen
Recombinant full-length human MMP3 protein
Target Antigen
MMP3
Clonality
Monoclonal
Clone
MMP3/1730
Type
Primary
Source
Animal
Origin
Animal
Positive Control
A431 cells. Prostate or Lung Carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
57 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL?

The catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL is BNC041730-100.

What sizes are available for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL in stock?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL?

The safety data sheet for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e0ffe0b/msds/bnc041730-100.pdf.

What is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1730), CF405S conjugate, 0.1mg/mL used for?

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (L

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

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