Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL

Catalog number BNUM1748-50

Price for BNUM1748-50

Size / count 1x 50 µL

About this product

Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM1748-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: UBB
Gene ID: 7314
NCBI Gene ID: 356190; 520348
UniProt: P0G47; P0G48; P62979; P62987; P62988
Swiss Prot: P0G47; P0G48; P62979; P62987; P62988
Host: Mouse
Species Reactivity: Human
Reactivity: Ubiquitin
Immunogen: Recombinant fragment of human Ubiquitin protein (around aa 1-119) (exact sequence is proprietary)
Target Antigen: Ubiquitin
Clonality: Monoclonal
Clone: UBB/1748
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, intracellular (verified) |IHC, FFPE (verified) |WB (verified)
Field of Research: Ubiquitination
Positive Control: MCF-7, HeLa or Jurkat cells. Alzheimer's Brain.
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 9 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2c, kappa
Species: Mus musculus (mouse)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL?

The catalog number for Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL is BNUM1748-50.

What sizes are available for Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL in stock?

Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL?

Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL?

Estimated delivery time for Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL?

The safety data sheet for Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Ubiquitin (Autophagy Marker) (UBB/1748), 1mg/mL used for?

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.