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Product details

MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL

Catalog number BNC941764-500

Price for BNC941764-500

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Size / count 1x 500 µL

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is down-regulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941764-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
82 kDa matrix metalloproteinase-9; 92 kDa type IV collagenase; CLG 4B; CLG4B; Collagenase Type 4 beta; Collagenase type IV 92 KD; EC 3.4.24.35; Gelatinase 92 KD; Gelatinase B; Gelatinase beta; GELB; Macrophage gelatinase; MANDP2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MMP9
Gene ID
4318
NCBI Gene ID
297413
UniProt
P14780
Swiss Prot
P14780
Host
Mouse
Species Reactivity
Human
Reactivity
MMP9
Immunogen
A synthetic peptide corresponding to amino acids 603-614 of human MMP-9
Target Antigen
MMP9
Clonality
Monoclonal
Clone
2C3
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Human spleen tissue or human heart tissue. U937 cells. Human PBL whole cell lysate.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
92 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL?

The catalog number for MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL is BNC941764-500.

What sizes are available for MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL?

MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL in stock?

MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL?

MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL?

The safety data sheet for MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MMP9 (Matrix Metalloproteinase 9) (2C3), CF594 conjugate, 0.1mg/mL used for?

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (L

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

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