Prostate Specific Antigen (PSA) (3E6), CF640R conjugate, 0.1mg/mL

About this product

Recognizes a single protein of 33-34 kDa, identified as the prostate specific antigen (PSA) . This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT) . A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This MAb makes an excellent pair with MAb A67-B/E3 for PSA tests. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC401777-500

Size / count

1x 500 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

Antigen; prostate-specific (APS) ; Gamma-seminoprotein; hK3; Kallikrein related peptidase 3; Kallikrein-3 (KLK3) ; KLK2A1; P-30 antigen; Semenogelase; Seminin

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

KLK3

Gene ID

354

NCBI Gene ID

171995

UniProt

P07288

Swiss Prot

P07288

Host

Mouse

Species Reactivity

Human

Reactivity

Prostate Specific Antigen|PSA

Immunogen

Human Prostate Specific Antigen (PSA)

Target Antigen

Prostate Specific Antigen | PSA

Clonality

Monoclonal

Clone

#3E6

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified)

Field of Research

Cancer, Endocrinology

Positive Control

PC12 cells. Normal prostate or prostate carcinoma.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

33-34 kDa

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF640R