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Product details

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL

Catalog number BNC471780-100

Price for BNC471780-100

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Size / count 1x 100 µL

About this product

CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC471780-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD8 antigen; alpha polypeptide (p32) ; T8/Leu-2 T-lymphocyte differentiation antigen; Ly3; LYT3; MAL; T-cell surface glycoprotein CD8 alpha chain
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CD8A
Gene ID
925
NCBI Gene ID
85258
UniProt
P01732
Swiss Prot
P01732
Host
Rabbit
Species Reactivity
Human
Reactivity
CD8A
Immunogen
Recombinant full-length human CD8a protein
Target Antigen
CD8A
Clonality
Polyclonal
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
HuT78 or hPBL. Tonsil
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
32 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL?

The catalog number for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL is BNC471780-100.

What sizes are available for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL in stock?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b2061270361e10a02f/msds/bnc471780-100.pdf.

What is CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), CF647 conjugate, 0.1mg/mL used for?

CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

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