CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1780-500

Price for BNCB1780-500

Size / count 1x 500 µL

About this product

CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB1780-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD8 antigen; alpha polypeptide (p32) ; T8/Leu-2 T-lymphocyte differentiation antigen; Ly3; LYT3; MAL; T-cell surface glycoprotein CD8 alpha chain
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD8A
Gene ID: 925
NCBI Gene ID: 85258
UniProt: P01732
Swiss Prot: P01732
Host: Rabbit
Species Reactivity: Human
Reactivity: CD8A
Immunogen: Recombinant full-length human CD8a protein
Target Antigen: CD8A
Clonality: Polyclonal
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HuT78 or hPBL. Tonsil
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 32 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL?

The catalog number for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL is BNCB1780-500.

What sizes are available for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL in stock?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), Biotin conjugate, 0.1mg/mL used for?

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.