CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL

Catalog number BNUM1780-50

Price for BNUM1780-50

Size / count 1x 50 µL

About this product

CD8 is a cell surface receptor expressed either as a heterodimer with the CD8 beta chain (CD8 alpha/beta) or as a homodimer (CD8 alpha/alpha) . A majority of thymocytes and a subpopulation of mature T cells and NK cells express CD8a. CD8 binds to MHC class 1 and through its association with protein tyrosine kinase p56lck plays a role in T cell development and activation of mature T cells. For mature T-cells, CD4 and CD8 are mutually exclusive, so anti-CD8, generally used in conjunction with anti-CD4. It is a useful marker for distinguishing helper/inducer T-lymphocytes, and most peripheral T-cell lymphomas are CD4 /CD8-. Anaplastic large cell lymphoma is usually CD4 and CD8-, and in T-lymphoblastic lymphoma/leukemia, CD4 and CD8 are often co-expressed. CD8 is also found in littoral cell angioma of the spleen. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUM1780-50
Size / count: 1x 50 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD8 antigen; alpha polypeptide (p32) ; T8/Leu-2 T-lymphocyte differentiation antigen; Ly3; LYT3; MAL; T-cell surface glycoprotein CD8 alpha chain
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD8A
Gene ID: 925
NCBI Gene ID: 85258
UniProt: P01732
Swiss Prot: P01732
Host: Rabbit
Species Reactivity: Human
Reactivity: CD8A
Immunogen: Recombinant full-length human CD8a protein
Target Antigen: CD8A
Clonality: Polyclonal
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: HuT78 or hPBL. Tonsil
Stability: 2 years
Concentration: 1 mg/mL
Buffer: PBS, no BSA, no azide
Molecular Weight: 32 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit)
Classification: PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate: Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL?

The catalog number for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL is BNUM1780-50.

What sizes are available for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL in stock?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL?

CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL?

Estimated delivery time for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL?

The safety data sheet for CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD8A (Cytotoxic- & Suppressor T-Cell Marker) (N/A), 1mg/mL used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.