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Product details
Catalog number BNCB1802-100
Price for BNCB1802-100
Size / count 1x 100 µL
This antibody is specific for the soluble form of CD40. It is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is expressed on B-lymphocytes, follicular dendritic cells, bone marrow-derived dendritic cells, thymic epithelium, and interdigitating cells in the T-cell zones of secondary lymphoid organs. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for CD40 / TNFRSF5 / CD40L-Receptor (T8P2G4*A6), Biotin conjugate, 0.1mg/mL is BNCB1802-100.
CD40 / TNFRSF5 / CD40L-Receptor (T8P2G4*A6), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
CD40 / TNFRSF5 / CD40L-Receptor (T8P2G4*A6), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
CD40 / TNFRSF5 / CD40L-Receptor (T8P2G4*A6), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for CD40 / TNFRSF5 / CD40L-Receptor (T8P2G4*A6), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for CD40 / TNFRSF5 / CD40L-Receptor (T8P2G4*A6), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
This antibody is specific for the soluble form of CD40. It is a receptor on antigen-presenting cells of the immune system and is essential for mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germ
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.
If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.
