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Product details

Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL

Catalog number BNC401816-500

Price for BNC401816-500

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Size / count 1x 500 µL

About this product

Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC401816-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
HANP1; His1; HisC; HIST1; HIST1H1A; HIST1H1B; HIST1H1C; HIST1H1D; HIST1H1E; HIST1H1T; Oocyte-specific histone H1; Testicular H1 histone
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
H1
Gene ID
3005
NCBI Gene ID
226117 & 97358
UniProt
Multiple
Swiss Prot
Multiple
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Reactivity
Histone H1
Immunogen
Recombinant full-length human Histone H1 protein
Target Antigen
Histone H1
Clonality
Polyclonal
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, intracellular (verified) |IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control
HeLa, A-431, LNCap or Jurkat cells. Breast carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~30 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL?

The catalog number for Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL is BNC401816-500.

What sizes are available for Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL?

Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL in stock?

Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL?

Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Histone H1 (Pan Nuclear Marker) (N/A), CF640R conjugate, 0.1mg/mL used for?

Eukaryotic histones are basic and water-soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form t

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

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