Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL

Catalog number BNC471821-500

Price for BNC471821-500

Size / count 1x 500 µL

About this product

Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2 -dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG) . BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471821-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: C-type lectin domain family 4 member K; CD207; CLEC4K; Langerhans cell specific c type lectin; Langerin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD207
Gene ID: 50489
NCBI Gene ID: 199731
UniProt: Q9UJ71
Swiss Prot: Q9UJ71
Host: Mouse
Species Reactivity: Human
Reactivity: CD207|Langerin
Immunogen: Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
Target Antigen: CD207 | Langerin
Clonality: Monoclonal
Clone: LGRN/1821
Type: Primary
Source: Animal
Origin: Animal
Positive Control: HeLa or A549 cells (WB).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 48 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL?

The catalog number for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL is BNC471821-500.

What sizes are available for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL in stock?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b0061270361e109458/msds/bnc471821-500.pdf.

What is Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF647 conjugate, 0.1mg/mL used for?

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.