Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL

Catalog number BNC941821-500

Price for BNC941821-500

Size / count 1x 500 µL

About this product

Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2 -dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG) . BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC941821-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: C-type lectin domain family 4 member K; CD207; CLEC4K; Langerhans cell specific c type lectin; Langerin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CD207
Gene ID: 50489
NCBI Gene ID: 199731
UniProt: Q9UJ71
Swiss Prot: Q9UJ71
Host: Mouse
Species Reactivity: Human
Reactivity: CD207|Langerin
Immunogen: Recombinant fragment (around aa74-213) of human Langerin protein (exact sequence is proprietary)
Target Antigen: CD207 | Langerin
Clonality: Monoclonal
Clone: LGRN/1821
Type: Primary
Source: Animal
Origin: Animal
Positive Control: HeLa or A549 cells (WB).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 48 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF594

Frequently Asked Questions

What is the catalog number for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL?

The catalog number for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL is BNC941821-500.

What sizes are available for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL in stock?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL?

Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL?

The safety data sheet for Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Langerin / CD207 (Marker of Langerhans Cells) (LGRN/1821), CF594 conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.