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Product details

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL

Catalog number BNC881826-100

Price for BNC881826-100

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Size / count 1x 100 µL

About this product

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881826-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
95kDa melanocyte-specific secreted glycoprotein; M-beta; Melanocyte lineage specific antigen GP100; Melanocyte protein Pmel 17; Melanoma associated ME20 antigen; Melanosomal matrix protein17; p100; p26; PMEL17; Premelanosome protein; Secreted melanoma-associated ME20 antigen; SILV; Silver homolog
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
SILV
Gene ID
6490
NCBI Gene ID
95972
UniProt
P40967
Swiss Prot
P40967
Host
Rabbit
Species Reactivity
Human
Reactivity
Gp100|Melanosome|Pmel17|SILV
Immunogen
Recombinant full-length human SILV protein
Target Antigen
gp100 | Melanosome | Pmel17 | SILV
Clonality
Polyclonal
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
SK-MEL-28 cells. Melanoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
90-100 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL?

The catalog number for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL is BNC881826-100.

What sizes are available for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL in stock?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL?

Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e100024/msds/bnc881826-100.pdf.

What is Gp100 / Melanosome / PMEL17 / SILV (Melanoma Marker) (N/A), CF488A conjugate, 0.1mg/mL used for?

Cytotoxic T lymphocytes (CTLs) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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