PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL

Catalog number BNC041850-500

Price for BNC041850-500

Size / count 1x 500 µL

About this product

Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2) . Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator) . The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC041850-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B7 dendritic cell molecule; B7-DC; B7DC; Btdc; Butyrophilin B7DC; CD273; PD-L2; PDCD1L2; PDCD1LG2; PDL2; Programmed death ligand 2
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PDCD1LG2
Gene ID: 80380
NCBI Gene ID: 532279; 617872
UniProt: Q9Q51
Swiss Prot: Q9Q51
Host: Mouse
Species Reactivity: Human
Reactivity: CD273|PD-L2|PDCD1LG2
Immunogen: Recombinant fragment (around aa 27-220) of human PD-L2 protein (exact sequence is proprietary)
Target Antigen: CD273 | PD-L2 | PDCD1LG2
Clonality: Monoclonal
Clone: PDL2/1850
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow (verified)
Positive Control: Placenta or Pancreas. Thyroid Carcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 31 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL?

The catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL is BNC041850-500.

What sizes are available for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL?

PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL in stock?

PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL?

PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL?

The safety data sheet for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF405S conjugate, 0.1mg/mL used for?

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.