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Product details

PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL

Catalog number BNC881850-500

Price for BNC881850-500

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Size / count 1x 500 µL

About this product

Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2) . Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator) . The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC881850-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
B7 dendritic cell molecule; B7-DC; B7DC; Btdc; Butyrophilin B7DC; CD273; PD-L2; PDCD1L2; PDCD1LG2; PDL2; Programmed death ligand 2
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PDCD1LG2
Gene ID
80380
NCBI Gene ID
532279; 617872
UniProt
Q9Q51
Swiss Prot
Q9Q51
Host
Mouse
Species Reactivity
Human
Reactivity
CD273|PD-L2|PDCD1LG2
Immunogen
Recombinant fragment (around aa 27-220) of human PD-L2 protein (exact sequence is proprietary)
Target Antigen
CD273 | PD-L2 | PDCD1LG2
Clonality
Monoclonal
Clone
PDL2/1850
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow (verified)
Positive Control
Placenta or Pancreas. Thyroid Carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
31 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF488A

Frequently Asked Questions

What is the catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL?

The catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL is BNC881850-500.

What sizes are available for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL?

PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL in stock?

PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL?

PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL?

The safety data sheet for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), CF488A conjugate, 0.1mg/mL used for?

Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2) . Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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