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Product details
Catalog number BNUM1850-50
Price for BNUM1850-50
Size / count 1x 50 µL
Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2) . Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell survival. Conversely, engagement of CTLA4 by B7-1 or B7-2 may inhibit proliferation and IL-2 production. PD-L2 does not bind CD28, cytotoxic T lymphocyte A4 or ICOS (inducible co-stimulator) . The constitutive expression of PD-L1 and PD-L2 on parenchymal cells of heart, lung and kidney suggests that the Pdcd-1-Pdcd-L system could provide unique negative signaling to help prevent autoimmune disease. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), 1mg/mL is BNUM1850-50.
PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), 1mg/mL is available in the following size(s): 1x 50 µL.
PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), 1mg/mL is manufactured by Biotium.
Estimated delivery time for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for PD-L2 / PDCD1LG2 / CD273 (PDL2/1850), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Recognizes a protein of about 31 kDa, which is identified as PD-L2 (same as PDCD1LG2) . Engagement of CD28 by B7-1 (CD80) or B7-2 (CD86) in the presence of antigen promotes T cell proliferation, cytokine production, differentiation of effector T cells and the induction of Bcl-x, a promoter of T cell
A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.
Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.
Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.
