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Product details

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL

Catalog number BNUM1859-50

Price for BNUM1859-50

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Size / count 1x 50 µL

About this product

Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM1859-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Coagulation Factor VIII; Factor VIII Related Antigen; F8VWF; von Willebrand Antigen 2; von Willebrand Disease (vWD)
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
VWF
Gene ID
7450
NCBI Gene ID
440848
UniProt
P04275
Swiss Prot
P04275
Host
Rabbit
Species Reactivity
Human
Reactivity
Factor VIII Related-Ag|von Willebrand Factor
Immunogen
Recombinant fragment of human vWF protein (aa1815-1939) (exact sequence is proprietary)
Target Antigen
Factor VIII Related-Ag | von Willebrand Factor
Clonality
Recombinant Monoclonal
Clone
VWF/1859R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Hematology
Positive Control
HUVEC cells. Tonsil.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
250 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL?

The catalog number for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL is BNUM1859-50.

What sizes are available for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL?

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL in stock?

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL?

Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL?

Estimated delivery time for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL?

The safety data sheet for Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e1000f6/msds/bnum1859-50.pdf.

What is Von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) (VWF/1859R), 1mg/mL used for?

Von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and a

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

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