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Product details

MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL

Catalog number BNC401860-500

Price for BNC401860-500

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Size / count 1x 500 µL

About this product

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) . Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epithelium from particulate matter and microorganisms. Epithelial Mucins are large, secreted and cell surface glycoproteins crucial for adhesion modulation, signaling and epithelial cell protection. The number of repeats is highly polymorphic and varies among different alleles. The Mucin family consists of Mucins 1-4, Mucin 5 (AC and B), Mucins 6-8, Mucins 11-13 and Mucins 15-17. The Mucin 16 protein (also commonly referred to as CA125), encoded for by the gene MUC16, is a very high molecular weight tumor antigen consisting of three domains: a carboxy terminal domain, an extracellular domain and an amino terminal domain. Mucin 16, an ovarian cancer-associated antigen, is used as a marker to monitor the progress of epithelial ovarian cancer. It is a hydrophilic membrane-associated protein that may be involved in vitamin A functions. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC401860-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CA125; Cancer antigen 125; MUC16; Mucin16; Ovarian cancer-related tumor marker CA125; Ovarian carcinoma antigen CA125
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
CA125
Gene ID
94025
NCBI Gene ID
432676
UniProt
Q8WXI7
Swiss Prot
Q8WXI7
Host
Mouse
Species Reactivity
Human
Reactivity
CA125|MUC16
Immunogen
Full length native MUC16 protein Purified from human ovarian carcinoma
Target Antigen
CA125 | MUC16
Clonality
Monoclonal
Clone
MUC16/1860
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Mucins
Positive Control
MDA-MB-468 cells. Ovarian Cancer
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
>2,000 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL?

The catalog number for MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL is BNC401860-500.

What sizes are available for MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL?

MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL in stock?

MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL?

MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL?

The safety data sheet for MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MUC16 / CA125 (Ovarian Carcinoma Marker) (MUC16/1860), CF640R conjugate, 0.1mg/mL used for?

The mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) . Membrane-associated and secretory Mucins are high molecular weight glycoproteins of the glycocalyx (polysaccharide biofilm) that protects mucosal epith

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

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