AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL

Catalog number BNC401864-100

Price for BNC401864-100

Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 42 kDa, which is identified as Alpha-methylacyl-CoA Racemase (AMACR), also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells) . Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium) . AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC401864-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Alpha-methylacyl-CoA Racemase; AMACR; p504S; CBAS4; RACE
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: AMACR
Gene ID: 23600
NCBI Gene ID: 508343
UniProt: Q9UHK6
Swiss Prot: Q9UHK6
Host: Mouse
Species Reactivity: Human
Reactivity: AMACR
Immunogen: Recombinant human AMACR protein fragment (around aa 297-394) (exact sequence is proprietary)
Target Antigen: AMACR
Clonality: Monoclonal
Clone: AMACR/1864
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Field of Research: Cancer, Endocrinology, Metabolism
Positive Control: HEK cells. Prostate Adenocarcinoma.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 42 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF640R

Frequently Asked Questions

What is the catalog number for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL?

The catalog number for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL is BNC401864-100.

What sizes are available for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL?

AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL in stock?

AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL?

AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL?

The safety data sheet for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), CF640R conjugate, 0.1mg/mL used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.