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Product details

AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL

Catalog number BNUB1864-100

Price for BNUB1864-100

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Size / count 1x 100 µL

About this product

This antibody recognizes a protein of 42 kDa, which is identified as Alpha-methylacyl-CoA Racemase (AMACR), also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells) . Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium) . AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB1864-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Alpha-methylacyl-CoA Racemase; AMACR; p504S; CBAS4; RACE
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
AMACR
Gene ID
23600
NCBI Gene ID
508343
UniProt
Q9UHK6
Swiss Prot
Q9UHK6
Host
Mouse
Species Reactivity
Human
Reactivity
AMACR
Immunogen
Recombinant human AMACR protein fragment (around aa 297-394) (exact sequence is proprietary)
Target Antigen
AMACR
Clonality
Monoclonal
Clone
AMACR/1864
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Cancer, Endocrinology, Metabolism
Positive Control
HEK cells. Prostate Adenocarcinoma.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
42 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL?

The catalog number for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL is BNUB1864-100.

What sizes are available for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL?

AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL is available in the following size(s): 1x 100 µL.

Is AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL in stock?

AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL?

AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL?

Estimated delivery time for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL?

The safety data sheet for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 0.2mg/mL used for?

This antibody recognizes a protein of 42 kDa, which is identified as Alpha-methylacyl-CoA Racemase (AMACR), also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells o

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

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