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Product details
Catalog number BNUM1864-50
Price for BNUM1864-50
Size / count 1x 50 µL
This antibody recognizes a protein of 42 kDa, which is identified as Alpha-methylacyl-CoA Racemase (AMACR), also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells) . Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium) . AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 1mg/mL is BNUM1864-50.
AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 1mg/mL is available in the following size(s): 1x 50 µL.
AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 1mg/mL is manufactured by Biotium.
Estimated delivery time for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for AMACR / p504S (Prostate Cancer Marker) (AMACR/1864), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0296061270361e100202/msds/bnum1864-50.pdf.
This antibody recognizes a protein of 42 kDa, which is identified as Alpha-methylacyl-CoA Racemase (AMACR), also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and -oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells o
Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.
Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.
Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.
