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Product details
Catalog number BNUM1869-50
Price for BNUM1869-50
Size / count 1x 50 µL
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been reported in 97. 8 percent of scorable GIST's, including all c-kit negative GIST's. Overexpression of DOG-1 has been suggested to aid in the identification of GISTs, including Platelet-Derived Growth Factor Receptor Alpha mutants that fail to express c-kit antigen. The overall sensitivity of DOG1 and c-kit in GIST's is nearly identical: 94. 4% vs. 94. 7%. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (rDG1/447), 1mg/mL is BNUM1869-50.
DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (rDG1/447), 1mg/mL is available in the following size(s): 1x 50 µL.
DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (rDG1/447), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (rDG1/447), 1mg/mL is manufactured by Biotium.
Estimated delivery time for DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (rDG1/447), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for DOG-1 / TMEM16A (Gastrointestinal Stromal Tumor Marker) (rDG1/447), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Expression of DOG-1 protein is elevated in the gastrointestinal stromal tumors (GIST's), c-kit signaling-driven mesenchymal tumors of the GI tract. DOG-1 is rarely expressed in other soft tissue tumors, which, due to appearance, may be difficult to diagnose. Immunoreactivity for DOG-1 has been repor
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
