Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL

Catalog number BNC471881-500

Price for BNC471881-500

Size / count 1x 500 µL

About this product

Recognizes a protein of 30 kDa which is identified as Prohibitin, an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. Prohibitin is an ideal mitochondrial marker. It shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC471881-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB1; Prohibitin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PHB
Gene ID: 5245
NCBI Gene ID: 514303
UniProt: P35232
Swiss Prot: P35232
Host: Mouse
Species Reactivity: Human
Reactivity: Prohibitin
Immunogen: Recombinant human PHB protein fragment (aa167-261) (exact sequence is proprietary)
Target Antigen: Prohibitin
Clonality: Monoclonal
Clone: PHB/1881
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: HepG2, A431 or MCF-7, Ramos, Jurkat, K562 cells. Liver, Kidney, Heart or Endometrium.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~30 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2c, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL?

The catalog number for Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL is BNC471881-500.

What sizes are available for Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL?

Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL in stock?

Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL?

Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL?

The safety data sheet for Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b1061270361e109fb1/msds/bnc471881-500.pdf.

What is Prohibitin (Mitochondrial Marker) (PHB/1881), CF647 conjugate, 0.1mg/mL used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.