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Product details

Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1881-500

Price for BNCB1881-500

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Size / count 1x 500 µL

About this product

Recognizes a protein of 30 kDa which is identified as Prohibitin, an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. Prohibitin is an ideal mitochondrial marker. It shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1881-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB1; Prohibitin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PHB
Gene ID
5245
NCBI Gene ID
514303
UniProt
P35232
Swiss Prot
P35232
Host
Mouse
Species Reactivity
Human
Reactivity
Prohibitin
Immunogen
Recombinant human PHB protein fragment (aa167-261) (exact sequence is proprietary)
Target Antigen
Prohibitin
Clonality
Monoclonal
Clone
PHB/1881
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Positive Control
HepG2, A431 or MCF-7, Ramos, Jurkat, K562 cells. Liver, Kidney, Heart or Endometrium.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~30 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2c, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL?

The catalog number for Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL is BNCB1881-500.

What sizes are available for Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL?

Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL in stock?

Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL?

Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Prohibitin (Mitochondrial Marker) (PHB/1881), Biotin conjugate, 0.1mg/mL used for?

Recognizes a protein of 30 kDa which is identified as Prohibitin, an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle, maximum levels are detec

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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