Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL

Catalog number BNC881882-100

Price for BNC881882-100

Size / count 1x 100 µL

About this product

Recognizes a protein of 30 kDa which is identified as Prohibitin, an evolutionarily conserved protein with homologues found in yeast to man. It is located in the inner membrane of mitochondria. Although prohibitin mRNA and protein expression occurs throughout the cell cycle, maximum levels are detected during the G1/S phase transition and minimum levels are seen in S phase and the G2/mitosis boundary. Prohibitin is located exclusively in the mitochondria with the highest concentration on the inner membrane. Prohibitin is an ideal mitochondrial marker. It shows antiproliferative activity and has been proposed to play a role in normal cell cycle regulation, replicative senescence, cellular immortalization, and tumor suppression. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC881882-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: Epididymis luminal protein 215; Epididymis secretory sperm binding protein Li 54e; HEL 215; HEL S 54e; PHB; PHB1; Prohibitin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: PHB
Gene ID: 5245
NCBI Gene ID: 514303
UniProt: P35232
Swiss Prot: P35232
Host: Mouse
Species Reactivity: Human
Reactivity: Prohibitin
Immunogen: Recombinant human PHB protein fragment (aa167-261) (exact sequence is proprietary)
Target Antigen: Prohibitin
Clonality: Monoclonal
Clone: PHB/1882
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified) |WB (verified)
Positive Control: Ramos, Jurkat, HEK293, K562, HepG2, A431 or MCF-7 cell lysates (WB). Liver, Kidney, Heart or Endometrium (IHC).
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~30 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG1, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL?

The catalog number for Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL is BNC881882-100.

What sizes are available for Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL?

Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL in stock?

Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL?

Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL?

The safety data sheet for Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Prohibitin (Mitochondrial Marker) (PHB/1882), CF488A conjugate, 0.1mg/mL used for?

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.