Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL

Catalog number BNC041902-100

Price for BNC041902-100

Size / count 1x 100 µL

About this product

Recognizes a 33 kDa glycoprotein, identified as Nucleophosmin (NPM) . It is predominantly localized in the nucleus of cells in most tissues. NPM is involved in ribosomal assembly and rRNA transport. It is an abundant protein that is highly phosphorylated by Cdc2 kinase during mitosis. This phosphoprotein moves between the nucleus and the cytoplasm. It is thought to be involved in several processes including regulation of the ARF/p53 pathway. A number of genes are fusion partners, in particular the anaplastic lymphoma kinase gene on chromosome 2. Mutations in exon 12 affecting the C-terminus of the protein are associated with an aberrant cytoplasmic location. Mutations in this gene are associated with acute myeloid leukemia. The antibody may be a useful aid for classification of acute myeloid leukemia. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC041902-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: NO38; NPM; NPM1; Nucleolar phosphoprotein B23; Nucleolar protein NO38; Nucleophosmin (nucleolar phosphoprotein B23 numatrin) ; Nucleophosmin; Nucleophosmin/nucleoplasmin family member 1; Numatrin
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: NPM1
Gene ID: 4869
NCBI Gene ID: 557550
UniProt: P06748
Swiss Prot: P06748
Host: Mouse
Species Reactivity: Human
Reactivity: Nucleophosmin
Immunogen: Recombinant human NPM1 protein fragment (aa185-287) (exact sequence is proprietary)
Target Antigen: Nucleophosmin
Clonality: Monoclonal
Clone: NPM1/1902
Type: Primary
Source: Animal
Origin: Animal
Applications: IF (verified) |IHC, FFPE (verified) |WB (verified)
Positive Control: MCF-7, HeLa or A431 cells. Skin, Colon
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 33 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2b, kappa
Species: Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF405S

Frequently Asked Questions

What is the catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL?

The catalog number for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL is BNC041902-100.

What sizes are available for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL in stock?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL?

Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL?

The safety data sheet for Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is Nucleophosmin (Acute Myeloid Leukemia Marker) (NPM1/1902), CF405S conjugate, 0.1mg/mL used for?

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.