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Product details
Catalog number BNC881921-100
Price for BNC881921-100
Size / count 1x 100 µL
Thyroperoxidase (TPO) is a 933 amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1921), CF488A conjugate, 0.1mg/mL is BNC881921-100.
TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1921), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1921), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1921), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1921), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for TPO (Thyroid Peroxidase) (Thyroid Marker) (TPO/1921), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e101a4d/msds/bnc881921-100.pdf.
Thyroperoxidase (TPO) is a 933 amino acid, type I transmembrane glycoprotein that plays a key role in thyroid gland function and autoimmunity. It is present as a dimer on the apical surface of thyroid follicular cells. TPO functions in the iodination of tyrosine residues in thyroglobulin and phenoxy
Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.
Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.
Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.
