Product details
Catalog number BNC681944-500
Price for BNC681944-500
Size / count 1x 500 µL
TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity) . PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF568 conjugate, 0.1mg/mL is BNC681944-500.
TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF568 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.
TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF568 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF568 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF568 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF568 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e10209b/msds/bnc681944-500.pdf.
TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation act
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.