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Product details

TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL

Catalog number BNC941944-100

Price for BNC941944-100

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Size / count 1x 100 µL

About this product

TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation activity) . PTH has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart tissues. Studies have demonstrated that TIMP1 is useful as a biomarker for early detection of colorectal cancer, outperforming CEA. Additionally, TIMP1 studies have demonstrated its role in CRC tumorigenesis, as well as observing its overexpression in metastatic lymph nodes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC941944-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Clgi; Collagenase inhibitor; Collagenase inhibitor; Human; EPA; EPO; Erythroid Potentiating Activity; Erythroid-potentiating activity; Fibroblast collagenase inhibitor; FLJ90373; HCI; Human Collagenase Inhibitor; Metalloproteinase inhibitor 1; Metalloproteinase inhibitor 1 precursor; TIMP 1; TIMP; TIMP metallopeptidase inhibitor 1; TIMP-1; TIMP1 protein; Tissue Inhibitor of Metalloproteinase 1; Tissue inhibitor of metalloproteinases 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TIMP1
Gene ID
7076
NCBI Gene ID
522632
UniProt
P01033
Swiss Prot
P01033
Host
Rabbit
Species Reactivity
Human
Reactivity
TIMP1
Immunogen
Recombinant human full-length TIMP1 protein
Target Antigen
TIMP1
Clonality
Recombinant Monoclonal
Clone
TIMP1/1944R
Type
Primary
Source
Animal
Origin
Animal
Positive Control
293 cell extract or rat brain lysate. Human colon carcinoma.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
23 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF594

Frequently Asked Questions

What is the catalog number for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL?

The catalog number for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL is BNC941944-100.

What sizes are available for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL?

TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL in stock?

TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL?

TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL?

Estimated delivery time for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL?

The safety data sheet for TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd0299061270361e101293/msds/bnc941944-100.pdf.

What is TIMP1 (Colorectal and Lymph Node Metastasis Marker) (TIMP1/1944R), CF594 conjugate, 0.1mg/mL used for?

TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases -1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 is identical to EPA (erythroid-potentiation act

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

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