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Product details

Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL

Catalog number BNC401948-500

Price for BNC401948-500

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Size / count 1x 500 µL

About this product

This MAb recognizes a protein of 56. 5 kDa, identified as cytokeratin 10 (CK10) . CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC401948-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BCIE; BIE; EHK; Keratin Type I Cytoskeletal 10; KRT10
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT10
Gene ID
3858
NCBI Gene ID
99936
UniProt
P13645
Swiss Prot
P13645
Host
Rabbit
Species Reactivity
Cat, Dog, Human
Reactivity
Cytokeratin 10
Immunogen
Recombinant human full-length KRT10 protein
Target Antigen
Cytokeratin 10
Clonality
Recombinant Monoclonal
Clone
KRT10/1948R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
A431, HeLa, MCF7 cells. Esophagus or tonsil.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
56.5 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF640R

Frequently Asked Questions

What is the catalog number for Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL?

The catalog number for Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL is BNC401948-500.

What sizes are available for Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL?

Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL in stock?

Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL?

Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL?

Estimated delivery time for Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL?

The safety data sheet for Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e1016c6/msds/bnc401948-500.pdf.

What is Cytokeratin 10 (Suprabasal Epithelial Marker) (KRT10/1948R), CF640R conjugate, 0.1mg/mL used for?

This MAb recognizes a protein of 56. 5 kDa, identified as cytokeratin 10 (CK10) . CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layer

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

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