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Product details
Catalog number BNUM1951-50
Price for BNUM1951-50
Size / count 1x 50 µL
Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the transcriptional expression of different subsets of target genes. Bcl-6 allows GC B-cells to proliferate very rapidly in response to T-cell dependent antigens and tolerate the physiological DNA breaks required for immunglobulin class switch recombination and somatic hypermutation without inducing a p53/TP53-dependent apoptotic response. Antibodies to Bcl-6 are helpful in a number of diagnostic settings, for example in the differential diagnosis of small B-cell lymphoma, and in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) .Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), 1mg/mL is BNUM1951-50.
Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), 1mg/mL is available in the following size(s): 1x 50 µL.
Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), 1mg/mL is manufactured by Biotium.
Estimated delivery time for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), 1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for Bcl-6 (Follicular Lymphoma Marker) (BCL6/1951R), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.
Bcl-6 is a transcriptional repressor mainly required for germinal center (GC) formation and antibody affinity maturation which has different mechanisms of action specific to the lineage and biological functions. It forms complexes with different corepressors and histone deacetylases to repress the t
The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.
Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.
