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Product details

Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1963-100

Price for BNCB1963-100

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Size / count 1x 100 µL

About this product

Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1) . Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammatory and immune responses. Tryptases are released into the extracellular environment and are resistant to all known endogenous proteinase inhibitors. This antibody reacts with mast cells distributed in skin, synovium, lung, and heart. This antibody does not bind with any other cell type. Human mast cell tryptase is considered to be an important marker of mast cell activation and is an important mediator of inflammation. Mastocytosis is a term collectively used for a group of disorders in which there is abnormal accumulation of mast cells in one or multiple organs. Anti-tryptase, combined with anti-CD2, anti-CD25, and anti-CD117, can be useful in identifying reactive mast cell hyperplasia, myelogenous neoplasms, mast cell leukemia, and mastocytosis. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB1963-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
Lung Tryptase; Mast cell alpha II Tryptase; Mast cell beta I Tryptase; Mast cell protease 7; Mast cell protease II; MCP7; Pituitary Tryptase; Skin Tryptase; TPS1; TPSAB1; TPSB1; Tryptase 1; Tryptase alpha 1; Tryptase skin
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
TPSAB1
Gene ID
7177
NCBI Gene ID
405479
UniProt
Q15661
Swiss Prot
Q15661
Host
Mouse
Species Reactivity
Human
Reactivity
Tryptase
Immunogen
Recombinant human Tryptase protein fragment (around aa 115-233) (Exact sequence is proprietary)
Target Antigen
Tryptase
Clonality
Monoclonal
Clone
TPSAB1/1963
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Positive Control
Skin or Tonsil
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
31-36 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL?

The catalog number for Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL is BNCB1963-100.

What sizes are available for Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL?

Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL in stock?

Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL?

Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL?

The safety data sheet for Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029a061270361e10153c/msds/bncb1963-100.pdf.

What is Tryptase (Mast Cell Marker) (TPSAB1/1963), Biotin conjugate, 0.1mg/mL used for?

Tryptases comprise a family of trypsin-like serine proteases (peptidase family S1) . Tryptases are stored in mast cell secretory granules and basophils. Mast cells are connective tissue cells derived from blood-forming tissues that line arterial walls and secrete substances, which mediate inflammato

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

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