HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1985-500

Price for BNCB1985-500

Size / count 1x 500 µL

About this product

This MAb reacts with a protein of 22 kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine and sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the subunit is identical to that of thyroid stimulating hormone (TSH) follicle stimulating hormone (FSH), and luteinizing hormone (LH) . hCG MAb detects cells and tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma and adenocarcinoma of the lung demonstrate anti-hCG positivity in 90% and 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB1985-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CG-beta; CGB3; CGB5; CGB7; CGB8; Choriogonadotropin Subunit beta; hCGB
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: CGB
Gene ID: 1082
NCBI Gene ID: 172944
UniProt: P01233
Swiss Prot: P01233
Host: Rabbit
Species Reactivity: Human
Reactivity: HCG Beta
Immunogen: Recombinant full-length hCG beta protein
Target Antigen: HCG Beta
Clonality: Recombinant Monoclonal
Clone: HCGb/1985R
Type: Primary
Source: Animal
Origin: Animal
Applications: IHC, FFPE (verified)
Positive Control: JAR or TT Cells. Placenta
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 22 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL?

The catalog number for HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL is BNCB1985-500.

What sizes are available for HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL?

HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL in stock?

HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL?

HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is HCG-beta (Pregnancy & Choriocarcinoma Marker) (HCGb/1985R), Biotin conjugate, 0.1mg/mL used for?

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.