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Product details

Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL

Catalog number BNUM1990-50

Price for BNUM1990-50

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Size / count 1x 50 µL

About this product

This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10) . CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM1990-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
BCIE; BIE; EHK; Keratin Type I Cytoskeletal 10; KRT10
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
KRT10
Gene ID
3858
NCBI Gene ID
99936
UniProt
P13645
Swiss Prot
P13645
Host
Rabbit
Species Reactivity
Human, Mouse
Reactivity
Cytokeratin 10|KRT10
Immunogen
Recombinant human full-length KRT10 protein
Target Antigen
Cytokeratin 10 | KRT10
Clonality
Recombinant Monoclonal
Clone
KRT10/1990R
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer, Cytoskeleton
Positive Control
A431, HeLa, MCF7 cells. Esophagus or tonsil.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
56.5 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL?

The catalog number for Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL is BNUM1990-50.

What sizes are available for Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL?

Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL is available in the following size(s): 1x 50 µL.

Is Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL in stock?

Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL?

Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL?

Estimated delivery time for Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL?

The safety data sheet for Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029c061270361e10246f/msds/bnum1990-50.pdf.

What is Cytokeratin 10 (KRT10) (Suprabasal Epithelial Marker) (KRT10/1990R), 1mg/mL used for?

This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10) . CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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