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Product details

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL

Catalog number BNC471994-100

Price for BNC471994-100

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Size / count 1x 100 µL

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC471994-100
Size / count
1x 100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MGC126102; MGC126103; MGC126104; MMP 3; MMP-3; MMP3; Proteoglycanase; SL-1; SL1; STMY; STMY1; STR1; Stromelysin 1; Stromelysin-1; Transin 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MMP3
Gene ID
4314
NCBI Gene ID
375129
UniProt
P08254
Swiss Prot
P08254
Host
Rabbit
Species Reactivity
Human
Reactivity
MMP3
Immunogen
Recombinant fragment (around aa 317-327) of human MMP3 protein
Target Antigen
MMP3
Clonality
Recombinant Monoclonal
Clone
MMP3/1994R
Type
Primary
Source
Animal
Origin
Animal
Positive Control
Human prostate or lung tissue. A-431 cells.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
57 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL?

The catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL is BNC471994-100.

What sizes are available for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL in stock?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL?

The safety data sheet for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029e061270361e102de7/msds/bnc471994-100.pdf.

What is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), CF647 conjugate, 0.1mg/mL used for?

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (L

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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