MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL

Catalog number BNCB1994-100

Price for BNCB1994-100

Size / count 1x 100 µL

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB1994-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MGC126102; MGC126103; MGC126104; MMP 3; MMP-3; MMP3; Proteoglycanase; SL-1; SL1; STMY; STMY1; STR1; Stromelysin 1; Stromelysin-1; Transin 1
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name: MMP3
Gene ID: 4314
NCBI Gene ID: 375129
UniProt: P08254
Swiss Prot: P08254
Host: Rabbit
Species Reactivity: Human
Reactivity: MMP3
Immunogen: Recombinant fragment (around aa 317-327) of human MMP3 protein
Target Antigen: MMP3
Clonality: Recombinant Monoclonal
Clone: MMP3/1994R
Type: Primary
Source: Animal
Origin: Animal
Positive Control: Human prostate or lung tissue. A-431 cells.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 57 kDa
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG
Species: Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL?

The catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL is BNCB1994-100.

What sizes are available for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL in stock?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL?

The safety data sheet for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), Biotin conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.