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Product details

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL

Catalog number BNUB1994-500

Price for BNUB1994-500

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Size / count 1x 500 µL

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB) . MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUB1994-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CHDS6; Matrix metalloproteinase 3; Matrix metalloproteinase-3; MGC126102; MGC126103; MGC126104; MMP 3; MMP-3; MMP3; Proteoglycanase; SL-1; SL1; STMY; STMY1; STR1; Stromelysin 1; Stromelysin-1; Transin 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
MMP3
Gene ID
4314
NCBI Gene ID
375129
UniProt
P08254
Swiss Prot
P08254
Host
Rabbit
Species Reactivity
Human
Reactivity
MMP3
Immunogen
Recombinant fragment (around aa 317-327) of human MMP3 protein
Target Antigen
MMP3
Clonality
Recombinant Monoclonal
Clone
MMP3/1994R
Type
Primary
Source
Animal
Origin
Animal
Positive Control
Human prostate or lung tissue. A-431 cells.
Stability
2 years
Concentration
0.2 mg/mL
Buffer
PBS, 0.05% BSA, 0.05% azide
Molecular Weight
57 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG
Species
Oryctolagus cuniculus (domestic rabbit), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate
Purified, with BSA

Frequently Asked Questions

What is the catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL?

The catalog number for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL is BNUB1994-500.

What sizes are available for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL in stock?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL?

MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL?

Estimated delivery time for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL?

The safety data sheet for MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is MMP3 (Marker of Metastasis and Rheumatoid Arthritis) (MMP3/1994R), 0.2mg/mL used for?

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (L

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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