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Product details

IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL

Catalog number BNC042001-500

Price for BNC042001-500

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Size / count 1x 500 µL

About this product

This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110 kDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC042001-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD210 antigen; CDw210a; IBD28; IL10R alpha; IL-10R subunit 1; IL-10R1; IL10RA IL10RIL-10R subunit alpha; interleukin 10 receptor; alpha; interleukin-10 receptor alpha chain; Interleukin-10 receptor subunit 1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID
16154
NCBI Gene ID
379327
UniProt
Q61727
Swiss Prot
Q61727
Host
Rat
Species Reactivity
Mouse
Reactivity
IL-10R1
Immunogen
Purified recombinant extracellular region of Mouse IL10RA
Target Antigen
IL-10R1,
Clonality
Monoclonal
Clone
1B1.3a
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published)
Positive Control
MPBMC's. Spleen, Thymus, Lymph Node, Placenta, Lung or Liver.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
90-110 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (2008) 181:5545-5550. (neutralization) PLoS One (2017) 12(10): e0186317. (Flow, surface)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL?

The catalog number for IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL is BNC042001-500.

What sizes are available for IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL?

IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL in stock?

IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL?

IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL?

The safety data sheet for IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is IL-10R1, Mouse (Interleukin-10 Receptor 1) (CD210) (1B1.3a), CF405S conjugate, 0.1mg/mL used for?

This monoclonal antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110 kDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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