PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL

Catalog number BNC882002-100

Price for BNC882002-100

Size / count 1x 100 µL

About this product

PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally, Pdcd1mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC882002-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD279; CD279 antigen; PD1; PDCD1; Programmed cell death 1; Programmed cell death protein 1; Systemic lupus erythematosus susceptibility 2 (SLEB2)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: 18566
NCBI Gene ID: 5024
UniProt: Q02242
Swiss Prot: Q02242
Host: Rat
Species Reactivity: Mouse
Reactivity: PD1
Immunogen: PDCD1 transfected BHK cells
Target Antigen: PD1
Clonality: Monoclonal
Clone: RMP1-14
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |Functional studies (published)
Positive Control: Spleen, Thymus or Lymph Node.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~50-55 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (2005) 175:1586-1592. (Flow; functional studies) Cancer Res (2014) 74(14): 3652-8. (functional studies) Cancer Discov (2017) 7(7): 694-703. (functional studies)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF488A

Frequently Asked Questions

What is the catalog number for PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL?

The catalog number for PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL is BNC882002-100.

What sizes are available for PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL?

PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL in stock?

PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL?

PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL?

Estimated delivery time for PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL?

The safety data sheet for PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029d061270361e102a0d/msds/bnc882002-100.pdf.

What is PD1, Mouse (RMP1-14), CF488A conjugate, 0.1mg/mL used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.