PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2002-500

Price for BNCB2002-500

Size / count 1x 500 µL

About this product

PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally, Pdcd1mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2002-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD279; CD279 antigen; PD1; PDCD1; Programmed cell death 1; Programmed cell death protein 1; Systemic lupus erythematosus susceptibility 2 (SLEB2)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: 18566
NCBI Gene ID: 5024
UniProt: Q02242
Swiss Prot: Q02242
Host: Rat
Species Reactivity: Mouse
Reactivity: PD1
Immunogen: PDCD1 transfected BHK cells
Target Antigen: PD1
Clonality: Monoclonal
Clone: RMP1-14
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |Functional studies (published)
Positive Control: Spleen, Thymus or Lymph Node.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: ~50-55 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (2005) 175:1586-1592. (Flow; functional studies) Cancer Res (2014) 74(14): 3652-8. (functional studies) Cancer Discov (2017) 7(7): 694-703. (functional studies)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL?

The catalog number for PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL is BNCB2002-500.

What sizes are available for PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL?

PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL in stock?

PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL?

PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL?

The safety data sheet for PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is PD1, Mouse (RMP1-14), Biotin conjugate, 0.1mg/mL used for?

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.