PD1, Mouse (RMP1-14), 0.2mg/mL

Catalog number BNUB2002-500

Price for BNUB2002-500

Size / count 1x 500 µL

About this product

PD-1 is expressed on a subset of CD4-CD8-thymocytes, and on activated T and B cells. PD-1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The PD-1 ligands, PD-L1 (also known as B7-H1) and PD-L2 (B7-DC), are members of the B7 immunoglobulin superfamily. PD-1 is transiently expressed on CD4 and CD8 thymocytes as well as activated T and B-lymphocytes and myeloid cells. Additionally, Pdcd1mRNA is expressed in developing B-lymphocytes during the pro-B-cell stage. The RMP1-14 antibody has been reported to block the binding of PD-1 to its ligands (B7-H1 and B7-DC) and to inhibit T cell proliferation and cytokine production co-stimulated by macrophages (but not by dendritic cells and B cells) . Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNUB2002-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: CD279; CD279 antigen; PD1; PDCD1; Programmed cell death 1; Programmed cell death protein 1; Systemic lupus erythematosus susceptibility 2 (SLEB2)
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: 18566
NCBI Gene ID: 5024
UniProt: Q02242
Swiss Prot: Q02242
Host: Rat
Species Reactivity: Mouse
Reactivity: PD1
Immunogen: PDCD1 transfected BHK cells
Target Antigen: PD1
Clonality: Monoclonal
Clone: RMP1-14
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |Functional studies (published)
Positive Control: Spleen, Thymus or Lymph Node.
Stability: 2 years
Concentration: 0.2 mg/mL
Buffer: PBS, 0.05% BSA, 0.05% azide
Molecular Weight: ~50-55 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (2005) 175:1586-1592. (Flow; functional studies) Cancer Res (2014) 74(14): 3652-8. (functional studies) Cancer Discov (2017) 7(7): 694-703. (functional studies)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Purified, with BSA

Frequently Asked Questions

What is the catalog number for PD1, Mouse (RMP1-14), 0.2mg/mL?

The catalog number for PD1, Mouse (RMP1-14), 0.2mg/mL is BNUB2002-500.

What sizes are available for PD1, Mouse (RMP1-14), 0.2mg/mL?

PD1, Mouse (RMP1-14), 0.2mg/mL is available in the following size(s): 1x 500 µL.

Is PD1, Mouse (RMP1-14), 0.2mg/mL in stock?

PD1, Mouse (RMP1-14), 0.2mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures PD1, Mouse (RMP1-14), 0.2mg/mL?

PD1, Mouse (RMP1-14), 0.2mg/mL is manufactured by Biotium.

What is the estimated delivery time for PD1, Mouse (RMP1-14), 0.2mg/mL?

Estimated delivery time for PD1, Mouse (RMP1-14), 0.2mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for PD1, Mouse (RMP1-14), 0.2mg/mL?

The safety data sheet for PD1, Mouse (RMP1-14), 0.2mg/mL is available here: https://cdn.gentaur.com/products/37/68dd029b061270361e101ea9/msds/bnub2002-500.pdf.

What is PD1, Mouse (RMP1-14), 0.2mg/mL used for?

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.