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Product details

CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL

Catalog number BNC042004-500

Price for BNC042004-500

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Size / count 1x 500 µL

About this product

CD134 is a type I integral membrane protein. This receptor is expressed on activated CD4 and CD8 T cells and B cells. The CD134 binds to CD134 ligand (CD252) to provide a costimulatory signal that is independent of CD28. CD134 is involved in coordinating CD4 T cell selection, migration and cytokine differentiation in T helper (Th) 1 and Th2 cells. CD134 is also involved in the stimulation of T cells, T dependent humoral response and generation of optimal CD4 T cell responses in vivo and in vitro. CD134 is expressed on activated CD4 T lymphocytes, and its ligand, CD134L, is found preferentially on activated B cells. Engagement of CD134 with its ligand, CD134L, delivers a strong costimulatory signal to effector T cells. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC042004-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD134; IMD16; Lymphoid activation antigen (ACT35) ; OX40 cell surface antigen; OX40L receptor; TAX transcriptionally activated glycoprotein 1 receptor; Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) ; Txgp1l
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID
22163
NCBI Gene ID
13885
UniProt
P47741
Swiss Prot
P47741
Host
Rat
Species Reactivity
Mouse
Reactivity
CD134
Immunogen
Purified recombinant Mouse OX-40 antigen
Target Antigen
CD134,
Clonality
Monoclonal
Clone
OX-86
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published) |IF (published) |WB (published)
Positive Control
MPBMC's. Spleen, Thymus or Lymph Node.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
~50 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (2000) 164:2160-2169. (functional studies) Exp Med (2003) 198(5): 737-746. (Flow, surface) Am J Respir Crit Care Med (2010) 181: 688-698. (WB) J Leukoc Biol (2007) 81: 766-774. (IF)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF405S

Frequently Asked Questions

What is the catalog number for CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL?

The catalog number for CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL is BNC042004-500.

What sizes are available for CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL?

CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL in stock?

CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL?

CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL?

Estimated delivery time for CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL?

The safety data sheet for CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD134, Mouse (OX40) (OX-86), CF405S conjugate, 0.1mg/mL used for?

CD134 is a type I integral membrane protein. This receptor is expressed on activated CD4 and CD8 T cells and B cells. The CD134 binds to CD134 ligand (CD252) to provide a costimulatory signal that is independent of CD28. CD134 is involved in coordinating CD4 T cell selection, migration and cytokine

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

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