CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL

Catalog number BNC472005-500

Price for BNC472005-500

Size / count 1x 500 µL

About this product

Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4. 5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNC472005-500
Size / count: 1x 500 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B cell surface antigen CD40; CD40 type II isoform; p50; Bp50; CD40L receptor; CDW40; TRAP; IMD3; IGM; Tnfrsf5; HIGM1; GP39; T-BAM
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: 21939
UniProt: P27512
Swiss Prot: P27512
Host: Rat
Species Reactivity: Mouse
Reactivity: CD40
Immunogen: Purified recombinant Mouse CD40 fusion protein
Target Antigen: CD40
Clonality: Monoclonal
Clone: FGK45.5
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |Functional studies (published)
Positive Control: MPBMC's. Spleen, Thymus or Lymph Node.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 48 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Eur J Immunol (1999) 29: 2835-2841. (functional studies; Flow, surface)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Notes: Protect from light
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: CF647

Frequently Asked Questions

What is the catalog number for CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL?

The catalog number for CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL is BNC472005-500.

What sizes are available for CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL?

CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL in stock?

CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL?

CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02b1061270361e1099c6/msds/bnc472005-500.pdf.

What is CD40, Mouse (FGK45.5), CF647 conjugate, 0.1mg/mL used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.