CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2005-100

Price for BNCB2005-100

Size / count 1x 100 µL

About this product

Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4. 5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number: BNCB2005-100
Size / count: 1x 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Synonyms: B cell surface antigen CD40; CD40 type II isoform; p50; Bp50; CD40L receptor; CDW40; TRAP; IMD3; IGM; Tnfrsf5; HIGM1; GP39; T-BAM
UNSPSC: 41116161
UNSPSC Description: Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID: 21939
UniProt: P27512
Swiss Prot: P27512
Host: Rat
Species Reactivity: Mouse
Reactivity: CD40
Immunogen: Purified recombinant Mouse CD40 fusion protein
Target Antigen: CD40
Clonality: Monoclonal
Clone: FGK45.5
Type: Primary
Source: Animal
Origin: Animal
Applications: Flow, surface (published) |Functional studies (published)
Positive Control: MPBMC's. Spleen, Thymus or Lymph Node.
Stability: 2 years
Concentration: 0.1 mg/mL
Buffer: PBS, 0.1% BSA, 0.05% azide
Molecular Weight: 48 kDa
References & Citations: Note: References for this clone sold by other suppliers may be listed for expected applications. Eur J Immunol (1999) 29: 2835-2841. (functional studies; Flow, surface)
Shipping Conditions: RT (ND)
Storage Conditions: Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life: Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment: IgG2a, kappa
Species: Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification: 0.05% sodium azide (CAS 26628-22-8)
Conjugate: Biotin

Frequently Asked Questions

What is the catalog number for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL?

The catalog number for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is BNCB2005-100.

What sizes are available for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL?

CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.

Is CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL in stock?

CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL?

CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.