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Product details

CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2005-500

Price for BNCB2005-500

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Size / count 1x 500 µL

About this product

Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4. 5 can be used for blocking of CD40/CD154 interaction and forin vitroandin vivoactivation of CD40 expressing APCs. This MAb is shown to indirectly activate natural killer (NK) cells, producing significant antitumor and anti-metastatic effects. Effective in boosting immune responses against infectious agents and can potentially be used to treat chronic autoimmune inflammatory processes. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2005-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
B cell surface antigen CD40; CD40 type II isoform; p50; Bp50; CD40L receptor; CDW40; TRAP; IMD3; IGM; Tnfrsf5; HIGM1; GP39; T-BAM
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID
21939
UniProt
P27512
Swiss Prot
P27512
Host
Rat
Species Reactivity
Mouse
Reactivity
CD40
Immunogen
Purified recombinant Mouse CD40 fusion protein
Target Antigen
CD40
Clonality
Monoclonal
Clone
FGK45.5
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published)
Positive Control
MPBMC's. Spleen, Thymus or Lymph Node.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
48 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Eur J Immunol (1999) 29: 2835-2841. (functional studies; Flow, surface)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL?

The catalog number for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is BNCB2005-500.

What sizes are available for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL?

CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL in stock?

CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL?

CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL?

The safety data sheet for CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD40, Mouse (FGK45.5), Biotin conjugate, 0.1mg/mL used for?

Upon binding to its ligand CD154, CD40 acts as a costimulatory molecule for the activation of B cells, dendritic cells, monocytes, and other APCs. CD40 plays roles in B cell activation, differentiation, proliferation and Ig isotype switching as well as dendritic cell maturation. FGK4. 5 can be used

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

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