IL-4 (Interleukin-4), Mouse (11B11), CF488A conjugate, 0.1mg/mL

About this product

IL-4 is a pleiotropic cytokine produced by activated T cells, mast cells, and basophils. IL-4 is a potent lymphoid cell growth factor, which stimulates the growth and activation of certain B cells and T cells. IL-4 is important for regulation of T helper subset development. IL-4 is expressed primarily by activated Th2 cells and NK cells, and at lower levels by mast cells, and basophils. IL-4 signals through the IL-4R, and dendritic cell IL-12. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number

BNC882008-100

Size / count

1x 100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Synonyms

B cell growth factor 1 (BCGF1) ; B cell IgG differentiation factor; B-Cell Stimulatory Factor 1 (BSF1) ; Binetrakin; IGG1 induction factor; IL4; Il4e12; Interleukin 4 variant 2; Interleukin 4; isoform 1; Interleukin-4; Lymphocyte stimulatory factor 1; Pitrakinra

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene ID

16189

NCBI Gene ID

276360

UniProt

P07750

Swiss Prot

P07750

Host

Rat

Species Reactivity

Mouse

Reactivity

IL-4

Immunogen

Partially Purified native Mouse IL-4

Target Antigen

IL-4 ,

Clonality

Monoclonal

Clone

11B11

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, intracellular (published) |Functional studies (published) |ELISA (published)

Positive Control

Spleen, Thymus or Lymph Node.

Stability

2 years

Concentration

0.1 mg/mL

Buffer

PBS, 0.1% BSA, 0.05% azide

Molecular Weight

13-14 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. PNAS USA (1992) 89:6065-6069. (functional studies; ELISA) J Immunol (2005) 174:1063-1072. (ELISA, Flow)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Notes

Protect from light

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

0.05% sodium azide (CAS 26628-22-8)

Conjugate

CF488A