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Product details

CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL

Catalog number BNUM2009-50

Price for BNUM2009-50

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Size / count 1x 50 µL

About this product

CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally. This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNUM2009-50
Size / count
1x 50 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD4 (L3T4) ; CD4; CD4 Lymphocyte deficiency; included; Leu3; Ly-4; Lymphocyte antigen CD4; p55; T cell differentiation antigen L3T4; T-cell surface antigen T4/Leu-3; T-cell surface glycoprotein CD4
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID
12504
NCBI Gene ID
2209
UniProt
P06332
Swiss Prot
P06332
Host
Rat
Species Reactivity
Mouse
Reactivity
CD4
Immunogen
Mouse CTL clone V4
Target Antigen
CD4
Clonality
Monoclonal
Clone
GK1.5
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published)
Positive Control
Spleen, Thymus or Lymph Node.
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
55 kDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. Immunological Rev (1982) 74:29-56. (functional studies) J Immunol (2005) 175: 2357-2365. (Flow)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2b, kappa
Species
Rattus norvegicus (laboratory rat)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free

Frequently Asked Questions

What is the catalog number for CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL?

The catalog number for CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL is BNUM2009-50.

What sizes are available for CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL?

CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL is available in the following size(s): 1x 50 µL.

Is CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL in stock?

CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL?

CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL?

Estimated delivery time for CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL?

The safety data sheet for CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is CD4, Mouse (T-Cell Marker) (GK1.5), 1mg/mL used for?

CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosin

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

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