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Product details

NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL

Catalog number BNCB2010-500

Price for BNCB2010-500

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Size / count 1x 500 µL

About this product

NK1. 1 is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by theKlrb1c/NKR-P1Cgene. It is predominantly expressed as a disulfide-linked homodimer on NK cells however; it is also expressed on NK-T cells, a rare population of T lymphocytes. NK1. 1 is expressed in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allograftsin vivo. NK-1. 1 has also been shown to play a role in NK cell activation, IFN- production, and cytotoxic granule release. NK-1. 1 is commonly used as a mouse NK cell marker. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNCB2010-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
CD161 antigen-like family member C; CD161c; Killer cell lectin-like receptor subfamily B member 1C (Klrb1c) ; Klrb1f; Lymphocyte antigen 55c (Ly55c) ; Lymphocyte antigen 59; Natural killer cell surface protein P1-40; NK1.1; NKR-P1 40; NKR-P1.9; NKR-P1C; NKRP1
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
Klrb1c (Mouse)
Gene ID
17059
NCBI Gene ID
480764
UniProt
P27814
Swiss Prot
P27814
Host
Mouse
Species Reactivity
Mouse
Reactivity
CD161c|Klrb1c, |NK1.1
Immunogen
CD Mouse spleen and bone marrow cells enriched for NK-1 cells
Target Antigen
CD161c | Klrb1c, | NK1.1
Clonality
Monoclonal
Clone
PK136
Type
Primary
Source
Animal
Origin
Animal
Applications
Flow, surface (published) |Functional studies (published)
Positive Control
MPBMC's or Thymus or Lymph Node.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
KDa
References & Citations
Note: References for this clone sold by other suppliers may be listed for expected applications. J Exp Med (1993) 178: 223-229. (functional studies; Flow, surface)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin

Frequently Asked Questions

What is the catalog number for NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL?

The catalog number for NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL is BNCB2010-500.

What sizes are available for NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL?

NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL in stock?

NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL?

NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL?

Estimated delivery time for NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL?

The safety data sheet for NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL is available here: https://biotium.com/wp-content/uploads/2018/06/SDS-primary-antibodies.pdf.

What is NK1.1 / CD161c / Klrb1c, Mouse (PK136), Biotin conjugate, 0.1mg/mL used for?

NK1. 1 is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by theKlrb1c/NKR-P1Cgene. It is predominantly expressed as a disulfide-linked homodimer on NK cells however; it is also expressed on NK-T cells, a rare population of T lymphocytes. NK1. 1 is expressed in so

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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