Product details
Catalog number BNC472027-100
Price for BNC472027-100
Size / count 1x 100 µL
Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portions of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. A positive result with this MAb is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
The catalog number for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is BNC472027-100.
CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 100 µL.
CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.
CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.
Estimated delivery time for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.
The safety data sheet for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02ac061270361e10802f/msds/bnc472027-100.pdf.
Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellula
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No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
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