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Product details

CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL

Catalog number BNC472027-500

Price for BNC472027-500

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Size / count 1x 500 µL

About this product

Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellular portions of these molecules have protein phosphatase activity and are involved in regulation of transmembrane signals. Antibody to CD45 is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms. A positive result with this MAb is highly indicative of lymphoid or myeloid origin. Certain types of lymphoid neoplasms may lack CD45 (Hodgkin lymphoma, some T-cell lymphomas, and some leukemias) so its absence does not rule out a hematolymphoid tumor. This antibody is expressed almost exclusively by cells of hematopoietic lineage and is present in most benign and malignant lymphocytes as well as plasma cell precursors. Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Specifications

Catalog number
BNC472027-500
Size / count
1x 500 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Synonyms
B220; CD45R; GP180; Leukocyte common antigen (LCA) ; Loc; Ly-5; Lyt-4; Protein tyrosine phosphatase receptor type C (PTPRC) ; Receptor-type tyrosine-protein phosphatase C; T200 glycoprotein
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
PTPRC
Gene ID
5788
NCBI Gene ID
654514
UniProt
P08575
Swiss Prot
P08575
Host
Mouse
Species Reactivity
Human
Reactivity
CD45|LCA
Immunogen
Human recombinant full-length CD45 protein
Target Antigen
CD45 | LCA
Clonality
Monoclonal
Clone
PTPRC/1147 PTPRC/1460
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified) |WB (verified)
Field of Research
Immunology, Signal transduction
Positive Control
Ramos, U-698, or GA-10 cells. Tonsil
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
180-220 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Notes
Protect from light
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
CF647

Frequently Asked Questions

What is the catalog number for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL?

The catalog number for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is BNC472027-500.

What sizes are available for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL?

CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is available in the following size(s): 1x 500 µL.

Is CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL in stock?

CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL?

CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is manufactured by Biotium.

What is the estimated delivery time for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL?

Estimated delivery time for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL?

The safety data sheet for CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL is available here: https://cdn.gentaur.com/products/37/68dd02aa061270361e107654/msds/bnc472027-500.pdf.

What is CD45 / LCA (Leucocyte Marker) (PTPRC/1147 + PTPRC/1460), CF647 conjugate, 0.1mg/mL used for?

Recognizes the CD45 leukocyte common antigen (LCA) family which is comprised of at least four isoforms of membrane glycoproteins (220, 205, 190, 180 kDa) expressed on hematopoietic cell lines but absent on non-hematopoietic cell lines, normal and malignant non-hematopoietic tissues. The intracellula

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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